![]() ![]() If you have ever had breast cancer, or a cancer that you have been told is dependent on a sex hormone (unless this is why you have been prescribed medroxyprogesterone).If you have had any problems with the way your liver works, or if you have any problems with the way your kidneys work.If you have ever had a blood clot in your legs or lungs.If you have any vaginal bleeding other than your normal monthly period.If you have any of the following conditions: migraines, asthma, epilepsy, diabetes, or high blood pressure.If you have a problem with your arteries, called arterial disease.For these reasons, before you start taking medroxyprogesterone tablets, it is important that your doctor knows: Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. See the separate leaflets called Medroxyprogesterone injection for contraception and Oestrogen and progestogen for HRT. There are other medicine leaflets available which will give you more information about medroxyprogesterone when it is used for these reasons. Medroxyprogesterone is also available as an injection to prevent pregnancy, and as tablets (in combination with an oestrogen) for hormone replacement therapy (HRT) during the menopause. Medroxyprogesterone is also prescribed (although at higher doses than in the conditions mentioned above) to help treat some cancers, particularly endometrial cancer. This means the patches of endometriosis also shrink. ![]() Medroxyprogesterone reduces the effect of oestrogen on these cells which causes them to 'shrink'. The cells in this tissue need oestrogen (another female sex hormone) to grow and survive. Endometriosis is a condition where tissue that normally lines the inside of your womb (uterus) is found elsewhere in your body, often in the pelvic area or tummy (abdomen). Medroxyprogesterone is also used for endometriosis. When it is prescribed to help problems such as heavy, painful, irregular or missed periods, it works by replacing or supplementing the naturally produced female sex hormone called progesterone. Medroxyprogesterone belongs to a group of medicines called progestogens, which are female hormones. Irregular or missed periods, endometriosis, and some cancers ![]()
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